Table 2. Intracellular proteins identified from two biological replicates of LPS-treated THP-1 cells by redox array.
Protein | Full name | Genbank | Biol. Rep 1 | Biol Rep 2 | Lost with DDT | Known |
---|---|---|---|---|---|---|
4-1BB/TNFRSF9 | Tumor necrosis factor receptor superfamily, member 9 | NM_001561 | ✓ | ✓ | ✓ | |
Activin B* | Activin B | NM_002193 | ✓ | ✓ | ||
Aldolase A | Aldolase A | NM_000034 | ✓ | ✓ | ✓ | |
ApoD | Apolipoprotein D | NM_001647 | ✓ | ✓ | ✓ | |
Beta Defensin 4 | Beta Defensin 4 | NM_004942 | ✓ | ✓ | ✓ | |
Biglycan | Biglycan | NM_001711 | ✓ | ✓ | ||
BIK | B-cell lymphocyte | NM_001197 | ✓ | ✓ | ||
BNIP2 | BCL2/adenovirus E1B 19 kDa protein-interacting protein 2 | NM_004330 | ✓ | ✓ | ✓ | |
Calbindin | Calbindin | NM_004929 | ✓ | ✓ | ✓ | |
CD79 alpha | CD79a molecule | NM_001783 | ✓ | ✓ | ✓ | |
CD 163 | Cluster of Differntiation 163 | NM_203416 | ✓ | ✓ | ||
Complement factor H* | Complement factor H | NM_000186 | ✓ | |||
Creatinine | Creatinine | N/A | ✓ | ✓ | ||
CSH1 | Chorionic somatomammotropin hormone 1 | NM_001317 | ✓ | ✓ | ✓ | |
CSK | Tyrosine-protein kinase CSK | NM_004383 | ✓ | ✓ | ||
Cytokeratin 18* | Cytokeratin 18 | NM_199187 | ✓ | ✓ | ✓ | |
DLL1* | Delta-like protein 1 | NM_005618 | ✓ | ✓ | ✓ | |
Endostatin | Endostatin; Collagen type 18 contains Endostatin | NM_030582 | ✓ | ✓ | ||
Endothelin Receptor A | Endothelin Receptor A | NM_001166055 | ✓ | ✓ | ||
FABP4 | Fatty acid binding protein 4 | NM_001442 | ✓ | ✓ | ✓ | ✓ |
FOXN3 | forkhead box N3 | NM_005197 | ✓ | ✓ | ||
Galectin-1* | Galectin-1 | NM_002305 | ✓ | ✓ | ✓ | ✓ |
GDF1 | GDF1 (N-term) | NM_001492 | ✓ | ✓ | ||
Ghrelin | Ghrelin | NM_016362 | ✓ | ✓ | ✓ | |
Glypican 3 | Glypican 3 | NM_00484 | ✓ | ✓ | ||
HADHA* | hydroxyacyl-CoA dehydrogenase | NM_000182 | ✓ | ✓ | ✓ | ✓ |
HCR/CRAM-A/B* | Human Chemokine Receptor CRAM-A isoform | NM_019052 | ✓ | ✓ | ||
Hepcidin | Hepcidin | NM_021175 | ✓ | ✓ | ||
HSP70 | Heat shock protein 70 | NM_005345 | ✓ | ✓ | ✓ | ✓ |
ICAM-2 | Intercellular Adhesion Molecule 2 | NM_000873 | ✓ | ✓ | ||
IL-11* | Interleukin 11 | NM_000641 | ✓ | ✓ | ✓ | |
IL-1 F5/FIL1delta | Human Interleukin 1 family member 5 | NM_173170 | ✓ | ✓ | ✓ | |
IL-17R* | Interleukin 17 receptor A | NM_014339 | ✓ | ✓ | ||
Integrin alpha V | Integrin alpha V | NM_002210 | ✓ | ✓ | ✓ | |
Itk | IL-2-inducible T cell kinase | NM_005546 | ✓ | ✓ | ✓ | |
ITM2B | Integral membrane protein 2B | NM_021999 | ✓ | ✓ | ✓ | |
LBP* | Human lipopolysaccharide-binding protein | NM 004139 | ✓ | ✓ | ✓ | |
LIF* | Leukemia Inhibitory Factor | NM_002309 | ✓ | ✓ | ||
LIGHT/TNFSF14* | hHomologous to lymphotoxins | NM_172014 | ✓ | ✓ | ||
Lep* | LEPTIN | NM_000230 | ✓ | |||
Lipocalin-2* | Lipocalin 2 | NM_005564 | ✓ | ✓ | ✓ | |
Livin | Livin | NM_139317 | ✓ | ✓ | ✓ | |
Lyn* | v-yes-1 Yamaguchi sarcoma viral related oncogene homoloc | NM_002350 | ✓ | ✓ | ✓ | |
MCSF/CSF1* | Macrophage-colony Stimuating Factor | NM_000757 | ✓ | ✓ | ||
NELL2 | neural epidermal growth factor-like 2 | NM_006159 | ✓ | ✓ | ✓ | |
Nesfatin* | Nesfatin | NM_005013 | ✓ | ✓ | ✓ | |
Neuropeptide Y | Neuropeptide Y | NM_000905 | ✓ | ✓ | ✓ | |
Omentin/Intelectin | Omentin/Intelectin | NM_017625.2 | ✓ | ✓ | ||
OPN* | Osteopontin | NM_000582 | ✓ | ✓ | ✓ | |
p21* | cyclin-dependent kinase inhibitor 1A | NM_078467 | ✓ | ✓ | ||
Pancreastatin* | Pancreastatin | NM_001275 | ✓ | ✓ | ✓ | |
PI 16* | Peptidase Inhibitor 16 | NM_153370 | ✓ | ✓ | ✓ | |
Podocalyxin* | Podocalyxin | NM_001018111 | ✓ | ✓ | ✓ | |
Prostasin* | Prostasin | NM_002773 | ✓ | ✓ | ✓ | |
RELMalpha/RELM beta | resistin-like alpha - Renamed RelmB in humans | NM_032579 | ✓ | ✓ | ✓ | |
S100A10 | S100A10, ANX2LG, CAL1L, CLP11 | NM_002966 | ✓ | ✓ | ||
S100A4 | S100 calcium-binding protein A4 | NM_002961 | ✓ | ✓ | ✓ | ✓ |
S-100b* | S100 calcium binding protein B | NM_006272 | ✓ | ✓ | ✓ | ✓ |
SART3 | squamous cell carcinoma antigen recognized by T-cells 3 | NM_014706 | ✓ | ✓ | ✓ | |
SCG3* | Secretogranin III | NM_013243 | ✓ | ✓ | ✓ | |
SLPI | antileukoproteinase (abbr.ALP) | NM_003064 | ✓ | ✓ | ||
SMAC | second mitochondria-derived activator of caspase | NM_019887 | ✓ | ✓ | ||
SRMS | Src-Related Kinase | NM_080823 | ✓ | ✓ | ✓ | |
SSEA-1* | Stage-Specific Embryonic Antigen1, CD15 | NM_002033 | ✓ | ✓ | ✓ | |
TGF-beta 5 | transforming growth factor-beta-5 | ✓ | ✓ | |||
BDCA-3* | Thrombomodulin | NM_000361 | ✓ | ✓ | ✓ | |
TNFSF3* | Lymphotoxin beta | NM_009588 | ✓ | ✓ | ✓ | |
TNK1* | tyrosine kinase, non-receptor, 1 | NM_003985 | ✓ | ✓ | ||
Troponin C* | troponin C type 1 | NM_003280 | ✓ | ✓ | ||
TXK | tyrosine-protein kinase TXK | NM_003328 | ✓ | ✓ | ✓ | |
Tyk2 | tyrosine kinase 2 | NM_003331 | ✓ | ✓ | ✓ | |
uPA* | Uurokinase plasminogen activator inducing activity | NM_002658 | ✓ | ✓ | ||
VDUP-1 | vitamin D3 up-regulated protein 1 | NM_006472 | ✓ | ✓ | ||
Vitamin D Receptor | Vitamin D Receptor | NM_000376 | ✓ | ✓ | ✓ |
*Indicates proteins identified only in cell lysates, but not in cell supernatants.