Table 3. Secreted proteins identified from two biological replicates of untreated THP-1 cells by redox array.
| Protein | Full name | Genbank | Biol. Rep 1 | Biol Rep 2 | Lost with DDT |
|---|---|---|---|---|---|
| 4-1BB/TNFRSF9 | Tumor necrosis factor receptor superfamily, member 9 | NM_001561 | ✓ | ✓ | ✓ |
| Aldolase A | Aldolase A | NM_000034 | ✓ | ||
| ApoD/Apolipoprotein D | Apolipoprotein D | NM_001647 | ✓ | ✓ | ✓ |
| Beta Defensin 4 | Beta Defensin 4 | NM_004942 | ✓ | ✓ | ✓ |
| Biglycan | Biglycan | NM_001711 | ✓ | ✓ | |
| BIK | B-cell lymphocyte | NM_001197 | ✓ | ✓ | ✓ |
| BNIP2 | BCL2/adenovirus E1B 19 kDa protein-interacting protein 2 | NM_004330 | ✓ | ✓ | |
| Calbindin | Calbindin | NM_004929 | ✓ | ✓ | ✓ |
| CD 163# | Cluster of Differntiation 163 | NM_203416 | ✓ | ✓ | ✓ |
| CD79 alpha | CD79a molecule | NM_001783 | ✓ | ✓ | ✓ |
| Contactin-1* | Contactin-1 | NM_001843 | ✓ | ✓ | ✓ |
| Creatinine | Creatinine | N/A | ✓ | ✓ | |
| CSK | Tyrosine-protein kinase CSK | NM_004383 | ✓ | ✓ | |
| Cystatin B* | Cystatin B | NM_000100 | ✓ | ✓ | ✓ |
| Endostatin | Endostatin; Collagen type 18 contains Endostatin | NM_030582 | ✓ | ✓ | |
| Endothelin Receptor A# | Endothelin Receptor A | NM_001166055 | ✓ | ||
| FABP4 | Fatty acid binding protein 4 | NM_001442 | ✓ | ✓ | |
| FOXN3 | Forkhead box N3 | NM_005197 | ✓ | ✓ | |
| GDF1 | GDF1 (N-term) | NM_001492 | ✓ | ✓ | |
| Ghrelin | Ghrelin | NM_016362 | ✓ | ✓ | ✓ |
| Glypican 3 | Glypican 3 | NM_00484 | ✓ | ✓ | |
| Hepcidin | Hepcidin | NM_021175 | ✓ | ||
| HSP70 | Heat shock protein 70 | NM_005345 | ✓ | ✓ | ✓ |
| ICAM-2 | Intercellular Adhesion Molecule 2 | NM_000873 | ✓ | ✓ | |
| IL-1 RII* | IL-1 Receptor II | NM_004633 | ✓ | ✓ | |
| IL-1 R4/ST2*,# | IL-1 R4/ST2 | NM_016232 | ✓ | ✓ | |
| Livin | Livin | NM_139317 | ✓ | ✓ | ✓ |
| Omentin/Intelectin | Omentin/Intelectin | NM_017625.2 | ✓ | ✓ | ✓ |
| RELM alpha/RELM beta | Resistin-like alpha - Renamed RelmB in humans | NM_032579 | ✓ | ✓ | ✓ |
| ROBO4*,# | Human Roundabout homolog 4 | NM_019055 | ✓ | ✓ | ✓ |
| S100A10 | S100A10, ANX2LG, CAL1L, CLP11 | NM_002966 | ✓ | ✓ | |
| S100A4 | S100 calcium-binding protein A4 | NM_002961 | ✓ | ✓ | ✓ |
| SLPI# | Antileukoproteinase (abbr.ALP) | NM_003064 | ✓ | ✓ | |
| SMAC# | Ssecond mitochondria-derived activator of caspase | NM_019887 | ✓ | ||
| TGF-alpha*,# | TGF-alpha. (transformed cell growth factor) | NM_003236 | ✓ | ||
| TGF-beta 5 | Transforming growth factor-beta-5 | ✓ | ✓ | ||
| TRAIL R3 (TNFRSF10C)' | TRAIL R3 (TNFRSF10C) | NM_003841 | ✓ | ✓ | |
| TRPC1* | Transient receptor potential cation channel, subfamily C | NM_003304 | ✓ | ||
| VDUP-1 | Vitamin D3 up-regulated protein 1 | NM_006472 | ✓ | ✓ | |
| Vitamin D Receptor | Vitamin D Receptor | NM_000376 | ✓ |
*indicates proteins identified only in cell supernatants, but not in cell lysates.
#indicates proteins identified in THP-1 cell supernatants treated with LPS, but not in supernatants from untreated THP-1 cells.