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. 2015 Mar 25;2(1):ENEURO.0031-14.2015. doi: 10.1523/ENEURO.0031-14.2015

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Copyright © 2015 Drion et al.

This is an open-access article distributed under the terms of the Creative Commons Attribution 4.0 International, which permits unrestricted use, distribution and reproduction in any medium provided that the original work is properly attributed.

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Fig. 8 — Colocalization of sensitivity curves, not activation curves, is crucial for robust compensation. a1, Activation functions (left) and sensitivity functions (right) of A-type potassium channels (blue), T-type calcium channels (red), and slow calcium channels (magenta). a2, Membrane potential variations over time before (left) and after a fivefold increase in slow calcium channel density (top right) and T-type calcium channel density (bottom right) in the presence of the compensation mechanism. b1, b2, Same as a1 and a2, respectively, after a right shift of 4.5 mV in A-type potassium channel activation function.