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KLF4 expression in human TM. (A) Representative immunoblot showing detection of KLF4 in normal cadaveric human TM tissue from a 42-year-old donor. (B) Immunolocalization of KLF4 in human trabecular meshwork from an 84-year-old donor. Representative images demonstrate KLF4 expression (red) throughout the TM as well as inner and outer walls of Schlemm's canal. Cell nuclei stained with DAPI (blue). AC, anterior chamber; SC, Schlemm's canal. Scale bar: 50 μm.
