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The relationship between percent iris area loss and the amount of pupil enlargement is shown for each eye in which the pupil increased 0.5 mm or more from light to dark condition. It can be seen that the amount of loss is approximately 8% per millimeter pupil increase, but that the variability of change is much higher in eyes with smaller pupil size increases (linear regression: y = 0.09 + 8.1x; r2 = 0.0002).
