Table 2.
Quantification of RGC survival in wild type, MMP-2 null (MMP-2−/−), and MMP-9 null (MMP-9−/−) mice, after ONC (4 dpi). RGC densities (RGCs/mm2) per retina are depicted. N, number of animals.
| Naive | ONC | |||||
|---|---|---|---|---|---|---|
| Wild type | MMP-2−/− | MMP-9−/− | Wild type | MMP-2−/− | MMP-9−/− | |
| 3393 | 3059 | 3551 | 2317 | 2327 | 2342 | |
| 3265 | 2928 | 3458 | 2473 | 2262 | 2663 | |
| 3660 | 3580 | 3481 | 2785 | 2606 | 2939 | |
| 3309 | 3810 | 3932 | 1952 | 2154 | 2695 | |
| 3187 | 3759 | 1825 | 2856 | 2641 | 3122 | |
| 3464 | 2938 | 2240 | 2463 | 2149 | 2880 | |
| 2192 | 2230 | 2663 | ||||
| 3209 | ||||||
|
| ||||||
| Mean | 3380 | 3346 | 2954 | 2475 | 2338 | 2813 |
| SEM | 68 | 169 | 316 | 134 | 77 | 99 |
| N | 6 | 6 | 7 | 6 | 7 | 8 |