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. 2015 Sep-Oct;32(5):533–535. doi: 10.4103/0970-2113.164170

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Copyright: © Lung India

This is an open access article distributed under the terms of the Creative Commons Attribution-NonCommercial-ShareAlike 3.0 License, which allows others to remix, tweak, and build upon the work non-commercially, as long as the author is credited and the new creations are licensed under the identical terms.

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Histopathological features: Photomicrographs showing a biphasic tumor with epithelial and spindle cells (a) (HE, ×200); epithelial component shows nuclear pleomorphism, frequent mitoses (b) (HE, ×400) and inflammatory infiltrate (c) (HE, ×400); sarcomatoid component shows fascicles of malignant spindle cells (d) (HE, ×400); immunohistochemistry for cytokeratin is positive in epithelial (e) and spindle cells (f) vimentin is positive in epithelial (g) and spindle cells (h) (IHC, ×200). TTF1 shows nuclear positivity (i) while p40 (j) EGFR E746-A750del (k) and L858R EGFR (l) are negative (IHC, ×400)