Table 5.
BaP
|
Testosterone
|
|||||
---|---|---|---|---|---|---|
Best affinity (kcal/mol) | Mean affinitya | Relative KD | Best affinity (kcal/mol) | Mean affinity | Relative KD | |
CYP1A | −14.5 | −14.3 | 0.026 | −11.6 | −9.5 | 0.127 |
CYP1B1 | −14.4 | −14.2 | 0.035 | −10.5 | −8.3 | 1.000 |
CYP1C1 | −14.1 | −13.7 | 0.072 | −11.0 | −8.9 | 0.363 |
CYP1C2 | −15.1 | −14.9 | 0.011 | −11.6 | −8.5 | 0.713 |
CYP1D1 | −12.5 | −12.2 | 1.000 | −10.7 | −9.9 | 0.065 |
Mean of top 5 poses.