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A, Representative examples of CPB1 IHC in luminal A grade 1 tumors. B, CPB1 levels in lymph node negative and positive luminal A grade 1 tumors in discovery (n = 48) and validation (n = 64) set of patients. The difference in CPB1 levels between lymph node positive and negative tumors was statistically significant in discovery but not in validation set although the trend is visible. Combining of both data sets (n = 112) would however lead to statistical significance at p = 0.02742.
