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. 2015 Sep 28;10(9):e0138531. doi: 10.1371/journal.pone.0138531

Fig 5. Colonoid gene expression changes induced by Poly I:C stimulation.

Fig 5

Colonoids were grown and stimulated as in Fig 2. Gene expression levels were determined using Nanostring probe-based analysis of isolated RNA. A) Fold change in normalized gene expression are grouped by category. Bars represent mean ±SEM compared to unstimulated samples. n = 6 (Poly I:C stimulation)/5 (unstim) duplicate samples. Discoveries (*) determined by false discovery rate following multiple t-test analysis. B) Heat map of the normalized probe counts of unstimulated and Poly I:C stimulated colonoids of each technical replicate. Samples and genes were clustered by Pearson correlation.