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. Author manuscript; available in PMC: 2016 Sep 1.
Published in final edited form as: Immunol Rev. 2015 Sep;267(1):259–282. doi: 10.1111/imr.12326

Figure 6. Comparison of the genomic organization of the cattle and human KIR loci.

Figure 6

Shown are the KIR genes and flanking LRC genes, comprising LILR and LAIR genes on the telomeric side, FCAR and NCR1 genes on the centromeric side. Each gene is represented by a schematic of the encoded protein in which each symbol represents an Ig-like domain and the type protein in which it is present: circle for KIR3DL, square for KIR3DX, triangle for LAIR, rhombus for FCAR, pentamer for NCR1, and hexagon for LILR. The encoded Ig-like domains of functional genes are colored green for KIR and yellow for other LRC genes. The encoded Ig-like domains of non-functional genes are shaded grey for KIR and white for LILR. This figure is adapted from Fig. 2 in Sanderson et al. (87).