Table 1.
Accepted organ specific criteria for antibody effects on allografts
Kidney | Heart | Pancreas | Lung | Liver | Bowel | |
---|---|---|---|---|---|---|
Hyperacute rejection | + | + | + | + | + | |
Acute humoral rejection | + | ± | ± | |||
Chronic humoral rejection | 1 | |||||
Accommodation1 | + | ± |
+, consensus established; ±, consensus in process: blank, no consensus.
The Banff classification uses the term ‘C4d deposition without morphological evidence of active rejection’ to indicate a state in which antidonor antibody reacts with the graft endothelium without causing overt injury.