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. Author manuscript; available in PMC: 2015 Sep 29.
Published in final edited form as: Osteoarthritis Cartilage. 2014 Oct;22(10):1724–1731. doi: 10.1016/j.joca.2014.06.021

Table 1.

The intra-rater and inter-rater reproducibilities (root-mean-square average coefficient of variation values [%]) of the variables.

Subchondral bone plate Trabecular bone Femur
Parameter Medial Lateral Medial Lateral Medial Lateral
Intra-rater reproducibility
GV 2.78 (2.23 – 3.56) 2.79 (2.24 – 3.58) 2.62 (2.10 – 3.36) 1.45 (1.16 – 1.86) 3.05 (2.45 – 3.92) 5.06 (4.05 – 6.49)
GV’ 7.13 (5.71 – 9.15) 6.68 (5.36 – 8.57) 13.99 (11.21 – 17.94) 8.91 (7.14 – 11.42) 9.53 (7.64 – 12.23) 8.36 (6.70 – 10.73)
GVnorm 2.77 (2.22 – 3.55) 2.69 (2.16 – 3.46) 2.70 (2.17 – 3.47) 1.56 (1.25 – 2.00) - -
LBP/C 3.33 (2.67 – 4.27) 4.71 (3.77 – 6.04) 1.45 (1.16 – 1.85) 1.93 (1.54 – 2.47) 1.37 (1.10 – 1.76) 2.68 (2.15 – 3.44)
HILap 2.17 (1.74 – 2.79) 2.46 (1.97 – 3.16) 1.64 (1.31 – 2.10) 1.98 (1.58 – 2.54) 1.32 (1.06 – 1.69) 1.88 (1.51 – 2.41)
HILBP 0.85 (0.68 – 1.09) 0.93 (0.75 – 1.19) 0.51 (0.41 – 0.65) 0.75 (0.60 – 0.96) 0.70 (0.56 – 0.90) 1.02 (0.82 – 1.31)
ELap 1.46 (1.17 – 1.87) 1.59 (1.27 – 2.04) 0.74 (0.59 – 0.95) 1.01 (0.81 – 1.29) 0.70 (0.56 – 0.89) 0.94 (0.75 – 1.20)
ELBP 0.42 (0.34 – 0.54) 0.56 (0.44 – 0.71) 0.23 (0.18 – 0.29) 0.26 (0.21 – 0.33) 0.29 (0.23 – 0.37) 0.35 (0.28 – 0.44)
Inter-rater reproducibility
GV 4.37 (3.50 – 5.60) 3.10 (2.49 – 3.98) 4.33 (3.47- 5.55) 2.51 (2.01 – 3.21) 4.75 (3.81 – 6.09) 6.11 (4.90 – 7.83)
GV’ 11.85 (9.50 – 15.21) 9.45 (7.58 – 12.13) 22.19 (17.79 – 28.47) 12.56 (10.07 – 16.11) 16.21 (13.00 – 20.80) 12.19 (9.77 – 15.64)
GVnorm 4.54 (3.64 – 5.82) 4.00 (3.21 – 5.13) 4.13 (3.31 – 5.30) 2.47 (1.98 – 3.17) - -
LBP/C 3.19 (2.55 – 4.09) 3.27 (2.62 – 4.19) 2.49 (2.00 – 3.20) 1.93 (1.55 -2.48) 2.21 (1.77 – 2.83) 3.20 (2.56 – 4.10)
HILap 1.74 (1.39 – 2.23) 1.90 (1.53 – 2.44) 2.48 (1.99 – 3.19) 2.05 (1.64 – 2.63) 1.51 (1.21 – 1.94) 2.04 (1.63 – 2.62)
HILBP 0.95 (0.76 – 1.22) 1.04 (0.84 – 1.34) 0.67 (0.53 – 0.85) 0.90 (0.72 – 1.15) 1.06 (0.85 – 1.35) 1.25 (1.00 – 1.60)
ELap 0.88 (0.70 – 1.13) 0.89 (0.71 – 1.14) 1.00 (0.80 – 1.28) 1.04 (0.84 – 1.34) 0.99 (0.79 – 1.27) 1.07 (0.86 – 1.37)
ELBP 0.57 (0.46 – 0.73) 0.52 (0.42 – 0.67) 0.31 (0.25 – 0.40) 0.29 (0.23 – 0.37) 0.41 (0.33 – 0.53) 0.39 (0.31 – 0.50)

Values in parentheses are the 95% confidence interval. GV = mean grayscale value, GV’ = soft tissue subtracted from GV, GVnorm = GV divided by the depth of the tibia, LBP/C = local binary patterns based contrast measure, HILap = homogeneity index from Laplacian-based image, HILBP = homogeneity index from LBP-based image, ELap = entropy from Laplacian-based image, and ELBP = entropy from LBP-based image.