Table 3.
Mean (SD) values of density-related and structure-related parameters in different KL grade groups from medial and lateral subchondral trabecular bone in tibia.
| Side | Parameter | KL0 (n=104) | KL1 (n=28) | KL2 (n=27) | KL3 (n=31) | KL4 (n=7) | p-value | Post-hoc* |
|---|---|---|---|---|---|---|---|---|
| Medial | GV | 105 (19) | 113 (15) | 121 (18) | 124 (18) | 135 (19) | <0.001 |
0-2, 0-3, 0-4, 1-3, 1-4 |
| GV’ | 60 (19) | 65 (17) | 70 (17) | 78 (16) | 87 (22) | <0.001 | 0-2, 0-3, 0-4, 1-3, 1-4, 2-4 |
|
| GVnorm | 18.3 (3.4) | 19.1 (2.6) | 20.5 (3.0) | 20.7 (3.1) | 22.5 (3.4) | <0.001 |
0-2, 0-3, 0-4, 1-3, 1-4 |
|
| LBP/C | 8.03 (0.88) | 8.19 (0.52) | 8.12 (0.85) | 7.84 (0.79) | 7.14 (0.90) | 0.031 | 0-4, 1-4, 2-4, 3-4 | |
| HILap | 0.72 (0.02) | 0.72 (0.03) | 0.72 (0.02) | 0.71 (0.02) | 0.70 (0.02) | 0.001 |
0-3, 0-4, 1-3, 1-4, 2-4 |
|
| HILBP | 0.48 (0.02) | 0.47 (0.02) | 0.47 (0.02) | 0.46 (0.02) | 0.44 (0.01) | <0.001 | 0-1, 0-2, 0-3, 0-4, 1-3, 1-4, 2-4, 3-4 |
|
| ELap | 7.07 (0.11) | 7.04 (0.11) | 7.03 (0.08) | 7.04 (0.10) | 7.01 (0.12) | 0.113 | - | |
| ELBP | 6.67 (0.09) | 6.73 (0.10) | 6.76 (0.08) | 6.77 (0.07) | 6.84 (0.06) | <0.001 |
0-1, 0-2, 0-3, 0-4, 1-3, 1-4, 2-4, 3-4 |
|
| Lateral | GV | 131 (16) | 135 (16) | 136 (14) | 128 (15) | 124 (19) | 0.148 | - |
| GV’ | 87 (13) | 87 (11) | 85 (12) | 82 (13) | 76 (17) | 0.169 | - | |
| GVnorm | 22.8 (2.7) | 22.8 (2.8) | 23.0 (2.4) | 21.4 (2.4) | 20.8 (3.5) | 0.039 | 0-3, 2-3, 2-4 | |
| LBP/C | 7.85 (0.77) | 7.88 (0.66) | 7.71 (0.80) | 7.78 (0.45) | 7.43 (1.10) | 0.531 | - | |
| HILap | 0.70 (0.02) | 0.70 (0.02) | 0.70 (0.02) | 0.70 (0.02) | 0.71 (0.02) | 0.144 | - | |
| HILBP | 0.45 (0.01) | 0.45 (0.02) | 0.44 (0.02) | 0.44 (0.01) | 0.43 (0.01) | <0.001 | 0-1, 0-2, 0-3, 0-4 | |
| ELap | 6.99 (0.10) | 6.96 (0.09) | 6.95 (0.10) | 6.97 (0.08) | 6.84 (0.11) | 0.002 | 0-4, 1-4, 2-4, 3-4 | |
| ELBP | 6.82 (0.06) | 6.85 (0.07) | 6.86 (0.06) | 6.86 (0.05) | 6.90 (0.03) | <0.001 | 0-1, 0-2, 0-3, 0-4 |
*
Differences between groups using Fisher’s LSD. Differences between groups using Bonferroni post-hoc test are bolded. GV = mean grayscale value, GV’ = soft tissue subtracted from GV, GVnorm = GV divided by the depth of the tibia, LBP/C = local binary patterns based contrast measure, HILap = homogeneity index from Laplacian-based image, HILBP = homogeneity index from LBP-based image, ELap = entropy from Laplacian-based image, and ELBP = entropy from LBP-based image.