Table 3. Type-specific amino acid mutations among the various groups of DENV-2 isolates.

Cosmopolitan						Asian-II		Asian-I	Asian/American		American
C-IA		C-IB	C-II	C-III
AA	Mut	-	-	AA	Mut	AA	Mut		AA	Mut	AA	Mut
130	R→K	-	-	108	L→M	1266	N→K	-	130	R→G	275	V→I
506	T→I	-	-	143	D→N	1301	V→A	-	1231	T→A	351	A→D
862	T→S	-	-	892	T→A	1662	R→K	-	1236	V→A	361	S→I
1243	I→T	-	-	906	Q→H	1820	N→S	-	1444	I→V	670	N→D
1301	V→I	-	-	1047	K→R	2355	L→F	-	1504	K→R	848	P→S
2891	T→A	-	-	1298	I→T				1536	K→R	887	K→R
3352	K→R	-	-						2418	V→I	1032	N→S
									2647	V→I	1242	T→S
									2736	R→K	1407	E→D
									3327	I→V	1842	A→T
											1856	K→R
											1941	K→R
											2042	I→T
											2043	K→R
											2444	I→V
											2670	C→V
											2684	K→V
											3044	V→I
											3049	E→A
											3129	T→S
											3138	L→V
											3219	V→T
											3291	R→S
											3310	Q→L
Total	7	0	0		6		5			10		52

Footnote: AA: Amino acid, C-IA: Cosmopolitan IA, C-IB: Cosmopolitan IB, C-II: Cosmopolitan II, C-III: Cosmopolitan III, Mut; mutation