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. 2015 Sep 28;8:484. doi: 10.1186/s13104-015-1405-4

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© Michaelis et al. 2015

Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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Fig. 1 — Effects of tozasertib and alisertib on the viability of non-ABCG2-expressing UKF-NB-3 cells, UKF-NB-3 cells transduced with a lentiviral vector encoding for ABCG2 (UKF-NB-3^ABCG2), or UKF-NB-3 cells transduced with a control vector (UKF-NB-3^iG2) in the absence or presence of the ABCG2 inhibitor WK-X-34 (2.5 µM) as determined by MTT assay after 120 h of incubation. WK-X-34 (2.5 µM) alone did not affect cell viability (Additional file 1: Table S1). *P < 0.05 relative to IC₅₀ UKF-NB-3 in the absence of WK-X-34