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. 2015 Sep 29;19:349. doi: 10.1186/s13054-015-1066-7

Table 3.

RCA-CVVHD flows and citrate dose at start of treatment and end of observation

Normal liver function (bilirubin ≤2 mg/dl) Mild liver failure (bilirubin 2–7 mg/dl) Severe liver failure (bilirubin ≥7 mg/dl)
Start End Start End Start End
Blood flow (ml/min) 109 ± 24 114 ± 25 109 ± 25 117 ± 28 110 ± 24 107 ± 20
Dialysate flow (ml/h) 2144 ± 502 2292 ± 500 2128 ± 405 2328 ± 567 2098 ± 403 2319 ± 501
Net ultrafiltration (ml/h) 77 ± 108 74 ± 114 68 ± 100 84 ± 105 84 ± 103 85 ± 102
Citrate dose (mmol/L blood) 4.0 ± 0.1 3.8 ± 0.2 4.0 ± 0.1 3.9 ± 0.3 4.0 ± 0.1 4.1 ± 0.4

RCA-CVVHD regional citrate anticoagulation and continuous venovenous hemodialysis

Mean ± SD. For dialysate to blood flow ratio and calcium dose, see Figs. 2 and 3, respectively