Table 1.

Mitochondrial respiratory function in CON, MV, and MV-EX animals

	CON	MV	MV-EX
State 3 respiration, nmol O2 · mg−1 · min−1	234.3 ± 13.5	212.4 ± 7.5	192 ± 2.1*
State 4 respiration, nmol O2 · mg−1 · min−1	43.4 ± 1.3	61.8 ± 5.6†	38.5 ± 3.1
RCR	5.4 ± 0.33	3.6 ± 0.33†	5.1 ± 0.32

Values are means ± SE. These data were obtained using pyruvate/malate as substrate. CON, control; MV, mechanical ventilation; MV-EX, mechanical ventilation and exercise trained; RCR, respiratory control ratio.

^*P < 0.05, MV-EX significantly different from CON.

^†P < 0.05, MV significantly different than CON and MV-EX.