Fig. 4.

Mean intake of water and caffeinated solution in NHE3^loxlox (Con) and NHE3^loxloxCre mice under basal conditions with access to water alone (basal) and over a 2-wk experimental period (exp) with choice of water or caffeinated solution (0.3 g/liter). Total fluid and food intake increased in both genotypes during the experimental period; however, no difference in the consumption of caffeinated solution, fluid, or food were observed, and the changes in total fluid consumption, food intake, and body weight were comparable between genotypes. n = 12/genotype; ^#P < 0.05 vs. basal same genotype.