Urinary flow rate and urinary excretions of Na+, K+, Cl−, glucose, Ca2+, Mg2+, total osmoles, and urinary pH in metabolic cage experiments of vehicle-treated (sterile water, 3% of body wt by oral gavage) or caffeine-treated (45 mg/kg body wt) NHE3loxlox (Con) and NHE3loxloxCre mice. n = 12/genotype; *P < 0.05 vs. Con;+ #P < 0.05 vs. vehicle same genotype.