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VPC01091 and FTY720 treatment improves lung function after ischemia-reperfusion (IR). Mice were pretreated with vehicle (Veh), VPC01091 (VPC), or FTY720 (FTY) 30 min before sham surgery or ischemia. Pulmonary artery pressure and pulmonary compliance were measured after 2 h of reperfusion. Results are presented as means ± SE. *P < 0.05 vs. vehicle sham, #P < 0.05 vs. vehicle IR, n = 5–7/group.
