Study B. (A) Clinical and (B) histologic severity of UD lesions in mice on the AIN76A diet and HFWD, regardless of supplementation with mineralized red algae (MS). (C) Clinical and (D) histologic severity of UD lesions in the HFWD groups without and with MS. UD lesions were scored (scale, 0 to 100) according to scratching, character of lesion, length of lesions, and body regions affected. The histologic severity of dermatitis lesions was scored as 1, minimal; 2, moderate; 3, or 4, marked. Values represent mean ± SEM. *, P < 0.05 (Student t test).