Table 3.
Median percent abundances of bacterial taxa in subjects with one versus multiple autoantibodies
| Taxaa | One autoantibody (n = 5) | Two to four autoantibodies (n = 16) | Unadjusted P valueb |
|---|---|---|---|
| Bacteria/Bacteroidetes/Bacteroidia/Bacteroidales/Bacteroidaceae/Bacteroides | 6.37 (5.67–6.96) | 35.62 (13.20–49.29) | 0.01 |
| Bacteria/Bacteroidetes/Bacteroidia/Bacteroidales/Prevotellaceae/Prevotella | 12.91 (9.62–26.77) | 0.05 (0.01–1.82) | 0.01 |
| Bacteria/Bacteroidetes/Bacteroidia/Bacteroidales/Porphyromonadaceae/Butyricimonas | 0.53 (0.28–0.54) | 0.23 (0.00–0.33) | 0.03 |
| Bacteria/Firmicutes/Clostridia/Clostridiales/Lachnospiraceae/Coprococcus | 1.37 (0.62–2.16) | 0.26 (0.09–1.02) | 0.03 |
| Bacteria/Firmicutes/Clostridia/Clostridiales/Lachnospiraceae/Butyrivibrio | 0.08 (0.04–0.44) | 0.00 (0.00–0.00) | <0.01 |
| Bacteria/Verrucomicrobia/Verrucomicrobiae/Verrucomicrobiales/Verrucomicrobiaceae/Akkermansia | 0.06 (0.02–0.08) | 0.74 (0.15–4.46) | 0.04 |
Data are median relative abundance of 16S rRNA sequences for bacterial clade. Shown in parentheses are the ranges of the bacterial abundance.
aPhylogeny of bacterial genera, assigned by 16S rRNA sequencing analysis.
bResults from Wilcoxon rank-based test.