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. 2015 Feb 2;26(10):2588–2598. doi: 10.1681/ASN.2014040404

Figure 4.

Figure 4.

Tolerant recipients have a higher number of B cells expressing GzmB and act in a dose-dependent manner. (A) Number of GZMB+ B cells per microliter of blood from HVs (n=6), TOLs (n=6), and STAs (n=6) (mean±SEM; *P<0.05). (B) Linear regression of percentage of GzmB+ B cells and percentage of inhibition of CD4+CD25− T cell proliferation (P<0.04). (C) Representative histograms for CD138, CD27, CD5, CD38, CD24, CD1d, IgD, IgG, and IgM expression within the GzmB+ (thin line) and GzmB− (thick line) in CD19+ B cells before stimulation. (D) Representative histograms for CD38 and CD138 within the GzmB+ (thin line) and GzmB− (thick line) in CD19+ B cells after stimulation.