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Histology of mice with doxorubicin nephropathy
| Mouse Model | Glomerular Compartment | Tubular Compartment | |||
|---|---|---|---|---|---|
| Glomeruli with Sclerosis (%) | Mesangial Expansion (1–3+) | Severity of Glomerular Epithelial Cell Hyperplasia (1–3) | Tubular Area with Protein Casts (%) | Interstitial Inflammation (1–3+) | |
| Luci.1309 | |||||
| 1 | 0 | 0 | 0 | 20 | 1 |
| 2 | 0 | 1 | 0 | 0 | 0 |
| 3 | 0 | 0 | 0 | 0 | 0 |
| sh3703 | |||||
| 1 | 40 | 2 | 2 | 60 | 3 |
| 2 | 60 | 3 | 2 | 20 | 3 |
| 3 | 60 | 3 | 2 | 80 | 3 |
| 4 | 20 | 1 | 1 | 20 | 1 |
| 5 | 60 | 3 | 2 | 80 | 3 |
| 6 | 60 | 3 | 2 | 20 | 3 |
| 7 | 20 | 3 | 1 | 40 | 2 |
