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Effects of Drp1 inhibitor mdivi-1 on the heart in mouse renal IR injury. (A) Apoptosis evaluated by Western blot analysis for activated caspase-3 was reduced by mdivi-1 treatment (n=6 per group). #P<0.05 versus sham. *P<0.05 versus IR 72 h. (B) Quantitative analysis of the fractional shortenings (FS) showed the protection of mdivi-1 (n=4–6 per group). #P<0.05 versus sham. *P<0.05 versus IR 72 h.
