Table 1.
Characteristics of ECD transplant recipients
| Characteristic | ESP Recipients (n=1870) | United States Recipients (n=1312) | P Value |
|---|---|---|---|
| Donor characteristics | |||
| Age (yr), median (q1, q3) | 69 (67, 73) | 69 (66, 71) | <0.001 |
| Age ≥70 yr | 882 (47)a | 462 (35) | <0.001 |
| Male sex | 879 (47) | 586 (45) | 0.19 |
| History of diabetes | 130 (7) | 109 (8) | 0.15 |
| History of hypertension | 989 (53) | 626 (48) | <0.01 |
| Cerebrovascular accident as cause of death | 1309 (70) | 1022 (78) | <0.001 |
| Recipient characteristics | |||
| Age (yr), median (q1, q3) | 66 (65, 69) | 60 (52, 67) | <0.001 |
| Age (yr) | <0.001 | ||
| ≥65 | 1520 (81) | 446 (34) | |
| 60–64 | 118 (6) | 271 (21) | |
| 55–59 | 64 (3) | 194 (15) | |
| 50–54 | 54 (3) | 152 (12) | |
| <50 | 114 (6) | 249 (19) | |
| Male sex | 1211 (65) | 785 (60) | <0.01 |
| Race | N/A | N/A | |
| White | 820 (63) | ||
| Black | 411 (31) | ||
| Other | 81 (6) | ||
| Cause of ESRD | <0.001 | ||
| Diabetes | 171 (9) | 412 (33) | |
| Other | 1699 (91) | 821 (67) | |
| Missing | N/A | 71 | |
| Body mass index (kg/m2) | <0.001 | ||
| <30 | 1464 (90) | 743 (75) | |
| ≥30 | 171 (10) | 247 (25) | |
| Missing | 235 | 322 | |
| Time on dialysis (yr) | <0.001 | ||
| Median (q1, q3) | 3.36 (1.97, 5.25) | 2.85 (1.69, 4.61) | |
| Peak panel reactive antibody (%) | <0.001 | ||
| <5 | 1802 (97) | 850 (70) | |
| 5–30 | 44 (2) | 237 (20) | |
| >30 | 20 (1) | 122 (10) | |
| Missing | 4 | 103 | |
| Cold ischemic time (hr) | <0.001 | ||
| 0–12 | 824 (46) | 135 (12) | |
| 12.1–24 | 875 (49) | 585 (53) | |
| >24 | 99 (5) | 392 (35) | |
| Missing | 72 | 199 | |
| Induction therapy | <0.001 | ||
| Depleting antibody | 264 (16) | 375 (31) | |
| Nondepleting antibody | 489 (31) | 388 (32) | |
| Neither | 839 (53) | 444 (37) | |
| Missing | 278 | 105 | |
| Calcineurin inhibitor | <0.001 | ||
| Tacrolimus | 426 (28) | 660 (58) | |
| Cyclosporine | 1056 (71) | 390 (34) | |
| Sirolimus | 16 (1) | 93 (8) | |
| Missing | 372 | 169 | |
| Antimetabolite | <0.001 | ||
| Mycophenolate mofetil | 1339 (90) | 963 (96) | |
| Azathioprine | 144 (10) | 40 (4) | |
| Missing | 387 | 309 |
N/A, not applicable.
a
Values represent n (%) unless otherwise specified.