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. 2015 Sep 29;12:29. doi: 10.1186/s12989-015-0104-6

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© Stoehr et al. 2015

Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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Fig. 1 — Evaluating cytotoxicity of ZnO nanoparticles under submerged and ALI conditions. A. Cytotoxicity as determined by LDH release assay. Data are presented as mean x-fold increase over untreated control (submerged) or NaCl-nebulized control (ALI) (dashed line). Error bars indicate the SEM of at least three independent experiments. A one-way analysis of variance (ANOVA) with a subsequent Tukey’s Multiple Comparison test was performed. Values were considered significantly different compared to the unexposed (submerged) or NaCl-nebulized (ALI) control or as indicated with p < 0.05 (*), p < 0.001 (**) and p < 0.0001 (***)