Table 3.

Intraclass correlation coefficients, mean bias and standard deviations of raw volumes (ml) and percentage difference (%) methods with lower and upper limits of agreement (LOA) for primaries and largest suspect cervical LN

Comparison	Volume	Intraclass correlation	Bias	Std. deviation	Lower LOA	Upper LOA
Diagnostic CT segmentation vs. cuboid approximation	Primary (ml)	0.60	+15.9	26.1	−35.3	+67.1
	Primary (%)	-	+54.1	22.5	+4.1	+104.1
	Largest LN (ml)	0.79	+2.9	17.4	−31.2	+37.0
	Largest LN (%)	-	+37.7	40.0	−40.7	+116.1
Diagnostic CT segmentation vs. ellipsoid approximation	Primary (ml)	0.88	−0.7	10.0	−20.3	+18.9
	Primary (%)	-	−8.0	27.8	−64.0	+48.0
	Largest LN (ml)	0.82	−13.5	31.6	−75.4	+48.4
	Largest LN (%)	-	−18.0	28.3	−72.0	+54.0
Diagnostic CT segmentation vs. radiotherapy-planning CT segmentation	Primary (ml)	0.74	+5.7	16.6	−26.9	+38.2
	Primary (%)	-	+28.1	56.0	−81.7	+137.9
	Largest LN (ml)	0.96	+0.2	8.2	−15.9	+16.2
	Largest LN (%)	-	+12.5	66.4	−117.6	+142.6

Due to proportional bias of the raw volume data, only percent difference values were applicable over a wide range of tumor and LN sizes