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. 2015 Sep 29;10(9):e0138365. doi: 10.1371/journal.pone.0138365

Table 1. PAH subject clinical characteristics and RV function.

Subjects Age Sex ERA PDE5 CCB PGI2 analogue Functional Class RVEF (%)
PAH01 42 F - sildenafil 20 mg nifedipine 30mg - II 50
PAH02 29 F bosentan 125 mg tadalafil 20 mg amlodipine 5 mg - II 53
PAH03 53 F ambrisentan 10 mg - amlodipine 2.5 mg - II 54
PAH04 48 M ambrisentan 10 mg tadalafil 20 mg - - I 40
PAH05 64 F bosentan 125 mg sildenafil 20 mg - iloprost 20mcg/ml I 47
PAH06 26 F bosentan 125 mg sildenafil 20 mg - - I 42
PAH07 29 F bosentan 62.5 mg sildenafil 20 mg - - I 40
PAH08 20 F ambrisentan 10 mg sildenafil 20 mg - - I 40
PAH09* 27 F - - - - II 41
PAH10 38 M - sildenafil 20 mg - - II 45

Abbreviations: ERA = Endothelin receptor antagonists. PDE-5 = Phosphodiesterase Type 5 inhibitor. CCB = Calcium channel blocker. PGI2 = prostacyclin. All medications are taken in the usual dosing schedule. PAH09 was not on pulmonary hypertension specific medication due to chronic thromboembolic pulmonary hypertension before surgery.