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. Author manuscript; available in PMC: 2016 Jun 1.
Published in final edited form as: Breast Cancer Res Treat. 2015 Apr 23;151(2):281–294. doi: 10.1007/s10549-015-3376-5

Fig. 5.

Fig. 5

Effect of LBH589 and salinomycin on tumorigenicity of TNBC cells. a Tumor volume change in NSG mice. Mice were treated with vehicle, LBH589, salinomycin, or a combination of LBH589 and salinomycin. Error bars represent mean ± SEM. b Final weight (g) of harvested tumors. Images show the tumors in each treatment condition. Scale bar: 2 cm. The error bars represent mean ± SEM. *p < 0.05. (c, d) Body weight (g) and food intake (g) per mouse were measured weekly. Error bars represent mean ± SEM. e IHC staining of Ki67 from harvested formalin-fixed tumors in each treatment condition. The upper panel shows representative images of each treatment condition. The lower panel shows the percentage of Ki67-positive cells in each treatment condition. Original magnifications were ×400. Error bars represent mean ± SD. *p < 0.05; **p < 0.005; ***p < 0.005