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. 2015 Sep 29;10(9):e0138979. doi: 10.1371/journal.pone.0138979

Table 5. Multiple salivary biomarkers and subject characteristics as predictors for cmetS-Z and cmetS-PCA in a randomly selected cohort (n = 726), stratified by WHO obesity status.

cmetS-Z cmetS-PCA
Estimate (95% CI) p value Estimate (95% CI) p value
Underweight and normal-weight children (n = 312)
Age (per year) 0.15 (-0.15–0.45) 0.33 0.30 (0.15–0.45) 0.0001
CRP (per SD) -0.04 (-0.23–0.16) 0.72 0.009 (-0.09–0.11) 0.86
Insulin (per SD) 0.11 (-0.35–0.59) 0.64 0.13 (-0.11–0.37) 0.29
Adiponectin (per SD) -0.21 (-0.37–-0.05) 0.01 -0.02 (-0.11–0.06) 0.57
Leptin (per SD) NA NA -0.03 (-0.15–0.23) 0.62
Fitness (poor vs. good)* 0.02 (-0.35–0.40) 0.90 0.04 (-0.15–0.23) 0.71
Overweight and obese children (n = 414)
Age (per year) 0.28 (-0.03–0.59) 0.08 0.36 (0.23–0.49) <0.0001
CRP (per SD) 0.28 (0.07–0.48) 0.01 0.18 (0.10–0.27) <0.0001
Insulin (per SD) 0.48 (0.32–0.65) <0.0001 0.19 (0.12–0.26) <0.0001
Adiponectin (per SD) -0.47 (-0.71–-0.22) 0.0002 -0.14 (-0.25–-0.04) 0.007
Leptin (per SD) NA NA 0.04 (-0.03–0.12) 0.28
Fitness (poor vs. good) 0.36 (-0.04–0.76) 0.07 0.25 (0.09–0.42) 0.003

*poor is defined as having values above the median, and good as having values below the median.