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. 2015 Sep 29;10(9):e0139142. doi: 10.1371/journal.pone.0139142

Table 2. Results of repeated measures analysis for sleep variables.

Data are presented as mean(±SD).

Control Resolved Unresolved Time Group Time x Group
Baseline Follow up Baseline Follow up Baseline Follow up F F F
Sleep Diary– 4–7 days
TSO (minutes) 635 (56) 613 (38) 619 (32) 614 (40) 611 (48) 593 (48) 2.6 1.5 0.3
Sleep Parameters PSG
SOL (minutes) 25 (25) 27 (29) 18 (11) 25 (28) 25 (30) 28 (17) 0.4 0.1 0.3
TST (minutes) 451 (38) 430 (43) 442 (35) 421 (58) 435 (38) 437 (42) 3.5 0.4 1.1
WASO (% of SPT) 7 (5) 10 (6) 6 (4) 12 (8) 7 (7) 8 (6) 9.4** 0.7 1.4
REM Latency (minutes) 113 (46) 141 (59) 111 (45) 187 (74) 123 (47) 140 (53) 14.5*** 1.9 2.8
N1 (% of TST) 8 (4) 7 (3) 8 (4) 6 (2) 10 (5) 7 (3) 10.1** 1.4 0.2
N2 (% of TST) 41 (5) 47 (6) 42 (6) 46 (6) 40 (8) 46 (8) 37.1*** 0.1 0.4
N3 (% of TST) 27 (5) 27 (5) 30 (6) 30 (7) 30 (6) 26 (5) 2.7 2.7 1.7
Total NREM (% of TST) 76 (5) 80 (4) 81 (3) 82 (4) 80 (3) 80 (5) 5.6* 5.3** a 2.3
REM (% of TST) 23 (5) 20 (4) 19 (3) 18 (4) 20 (3) 20 (5) 4.9* 4.9* b 1.9
SE (%) 88 (7) 85 (8) 90 (5) 82 (8) 87 (10) 87 (5) 6.3* 0.2 2.3

* p<0.05,

** p<0.01,

*** p<0.001.

a Control < Resolved;

b Control > Resolved

TSO = Total sleep opportunity; SOL = Sleep onset latency; TST = Total sleep time; WASO = Wake after sleep onset; SPT = Sleep period time; NREM = Non-Rapid Eye Movement, REM = Rapid Eye Movement; SE = Sleep efficiency