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. 2015 Sep 29;14:373. doi: 10.1186/s12936-015-0861-6

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© Papa Mze et al. 2015

Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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Fig. 3 — Prevalence of single, double, triple, quadruple and quintuple mutation, in Comoros and Senegal. The prevalence of single (S108N), double (S108N/C59R), triple (N51I/C59R/S108N), quadruple (N51I/C59R/S108N/A437G) and quintuple (N51I/C59R/S108N/A437G/K540E) mutation was determined by counting the number of mutants present only in one, two, three, four or five Codons respectively. The Z-test for two population proportions is used to determine the P values, with a significance level of α = 0.05