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. 2015 Sep 28;7:104. doi: 10.1186/s13148-015-0138-5

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© Sayar et al. 2015

Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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Fig. 4 — Methylation status of TAGLN in public datasets GSE20713 and GSE31979. a Graphs showing higher normalized average methylation scores (NAMS) for two probes of TAGLN in tumor tissues Mann–Whitney test, ****P < 0.0001. Horizontal lines: mean ± SEM. b Scatter plot showing correlation of average methylation scores of TAGLN probes (GSE20713) to average expression (log₂) of TAGLN probe sets (GSE20711); Spearman r = −0.5442, P < 0.0001. c ROC analyses for discrimination between healthy individuals and breast cancer patients, using TAGLN NAMSs. d Kaplan-Meier (KM) survival analysis showing higher RFS percentages for patients with tumor TAGLN NAMSs ≤80 (best cutoff among tested)