TABLE 1.
Characteristics of patients with laser-induced chrysiasis
| CASE | AGE RACE SEX | GOLD COMPOUND | GOLD ROUTE OF ADMINISTRATION | DURATION OF GOLD TREATMENT (years) | TOTAL AMOUNT OF GOLD ADMINISTERED (grams) | TIME AFTER LAST DOSE (years) | Q-SWITCHED LASER WAVELENGTH | SITE | TREATMENT | REFERENCE |
|---|---|---|---|---|---|---|---|---|---|---|
| 1 | 59 Caucasian Male | Sodium aurothiomalate | Intramuscular | 13 | 11.5 | 0[a] | Ruby 694nm[b] | Forehead | No | 3 |
| 2 | 40 Caucasian Female | Not reported | Intramuscular | >3 | 8.345 | 2–3 | Nd:YAG 1064nm | Cheeks | No | 24 |
| 3 | 49 Caucasian Female | Sodium aurothioglucose | Intramuscular | 10 | 4.3–13.0 | 1–3 | Ruby 694nm | Dorsal hands Forehead Thighs | No | 25 |
| 4 | 60 Caucasian Female | Sodium aurothioglucose | Intramuscular | Several | Not reported | 26 | Alexandrite 755nm [c] | Cheeks | Yes [d] | Current report |
| 5 | 70 Caucasian Female | Auranofin | Oral | 3 | Not reported | 20 | Alexandrite 755nm [e] | Cheeks Forehead | Yes [f] | 4 |
The patient had a 14-year history of granuloma faciale on his forehead that had been treated with intralesional corticosteroids and cryotherapy; thesetreatments resulted in hyperpigmentation of his forehead. He was still receiving gold when his foreheaad was treated with the laser.
The treatment settings were 25 nanoseconds, 6.53J/cm2, 2 pulses of 5mm spot diameter.
The treatment settings were 50 nanoseconds, 10–12J/cm2, 1 pulse of 10mm spot diameter.
The blue macules were successfully cleared by sequentially using a long-pulsed alexandrite laser, a nonablative fractional laser, and an ablative carbon dioxide laser.
The treatment settings were 50 nanoseconds, 3.5J/cm2, 15 pulses of 4mm spot diameter.
Almost complete resolution of the blue macules was observed 2 months after the second treatment of her face (each separated by 1 month) using the long-pulsed ruby laser (at a fluence of 35J/cm2, with a 10mm spot size and a chilled tip at 4°C).