Table 1.
Patient characteristics
| IPF | COPD | Control | p-value | p-value | p-value | |
|---|---|---|---|---|---|---|
| (n = 57) | (n = 20) | (n = 15) | IPF vs. Control | IPF vs. COPD | COPD vs. Control | |
| Age, years | 69.4 ± 8.5 | 70.8 ± 7.1 | 65.9 ± 7.9 | NS | NS | NS |
| Gender, male | 51 (89.5) | 19 (95.0) | 15 (100) | NS | NS | NS |
| Current or former smoker | 53 (93.0) | 20 (100) | 7 (46.7) | <0.001 | NS | <0.001 |
| Patients who underwent BAL | 25 (43.9) | – | – | |||
| Patients who underwent SLB | 10 (17.5) | – | – | |||
| FVC, % predicted | 84.2 ± 21.3 | 93.5 ± 20.1 | – | NS | ||
| DLCO, % predicted | 43.7 ± 14.2 | 56.6 ± 17.5 | – | 0.004 | ||
| 6MWD, m | 454 ± 108 | – | – | |||
| Minimum SpO2 during 6MWT, % | 85.7 ± 8.4 | – | – | |||
| PaO2 at room air, Torr | 82.6 ± 13.1 | – | – |
The data are presented either as the number (%) or mean ± standard deviation
IPF idiopathic pulmonary fibrosis, COPD chronic obstructive pulmonary disease, NS not significant, BAL bronchoalveolar lavage, BALF bronchoalveolar lavage fluid, SLB surgical lung biopsy, FVC forced vital capacity, DL CO diffusing capacity of the lung for carbon monoxide, 6MWD 6-minute walk distance, SpO 2 oxygen saturation, 6MWT 6-minute walk test, PaO 2 partial pressure of oxygen