Table 3.
Correlations between function measurements and serum matrix metalloproteinases in IPFa
| MMP-1 | MMP-2 | MMP-3 | MMP-7 | MMP-8 | MMP-9 | MMP-10 | MMP-12 | |
|---|---|---|---|---|---|---|---|---|
| %FVC | – | – | – | -0.308* | – | – | -0.344† | – |
| %DLCO | – | – | -0.251 | -0.316* | – | – | −0.434† | – |
| 6MWD | – | −0.355† | – | – | −0.228 | – | −0.384† | −0.309* |
| Minimum SpO2 during the 6MWT | – | – | −0.235 | −0.261 | – | – | −0.416† | – |
| PaO2 in room air | – | – | – | – | – | – | −0.318* | – |
The data are shown as Spearman’s ρ when the p-value < 0.10
IPF idiopathic pulmonary fibrosis, MMP matrix metalloproteinase, %FVC percentage of predicted forced vital capacity, %DL CO percentage of predicted diffusing capacity of the lung for carbon monoxide, 6MWD 6-minute walk distance, SpO 2 oxygen saturation, 6MWT 6-minute walk test, PaO 2 partial pressure of oxygen
aMMP-13 was excluded from the analysis
* p < 0.05, † p < 0.01