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. 2015 Sep 29;10(9):e0139620. doi: 10.1371/journal.pone.0139620

Fig 2. Upregulation of serum γ-glutamyl transpeptidase (GGT) in bile duct ligation animals induces reduction of bone mass.

Fig 2

(A) Bone mineral density of rat lower body (white square indicate analyzed area) at 2 w after operation measured by dual-energy X-ray absorptiometry (DEXA). SO, sham operated, control rats; BDL, rats with cholestatic liver disease treated by bile duct ligation; and AGT, BDL rats treated with intraperitoneal injection of GGT antibody (AGT3). (B) Representative μ-CT images of the distal femora of the rats in the SO, BDL, and AGT groups. White squares indicate the area analyzed. (C) Total bone density, (D) Mean cortical bone section area. Significant differences (*P < 0.05, ** P < 0.01) were observed between two experimental groups.