Table 3. SNPs associated with either schizophrenia or bipolar disorder with nominally significant p-values (<0.05).
| Comparison with control group (N = 502) | ||||||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Schizophrenia (N = 582) | BD-I (N = 180) | BD-II (N = 159) | Schizophrenia + BD-I (N = 762) | |||||||||||||
| SNP | P a | OR | CI | Best-fit model b | P a | OR | CI | Best-fit model b | P a | OR | CI | Best-fit model b | P a | OR | CI | Best-fit model b |
| rs3759915 | 0.245 | 0.843 | 0.632–1.124 | Recessive | 0.024* | 1.609 | 1.065–2.430 | Dominant | 0.317 | 0.790 | 0.498–1.253 | Recessive | 0.102 | 1.236 | 0.959–1.594 | Dominant |
| rs4777969 | 0.027* | 0.812 | 0.675–0.977 | Additive | 0.032* | 0.682 | 0.480–0.968 | Dominant | 0.213 | 0.785 | 0.537–1.149 | Dominant | 0.014* | 0.806 | 0.678–0.957 | Additive |
| rs8025225 | 0.412 | 0.870 | 0.623–1.215 | Recessive | 0.024* | 0.519 | 0.294–0.916 | Recessive | 0.621 | 1.102 | 0.749–1.623 | Dominant | 0.131 | 0.782 | 0.569–1.076 | Recessive |
| rs4777973 | 0.006* | 1.420 | 1.107–1.820 | Dominant | 0.135 | 1.311 | 0.919–1.871 | Dominant | 0.439 | 1.162 | 0.794–1.701 | Dominant | 0.004* | 1.405 | 1.113–1.774 | Dominant |
| rs11637898 | 0.003* | 1.443 | 1.130–1.843 | Dominant | 0.005* | 1.641 | 1.162–2.319 | Dominant | 0.484 | 0.770 | 0.370–1.601 | Recessive | 0.0006** | 1.492 | 1.186–1.878 | Dominant |
| rs4777980 | 0.015* | 1.261 | 1.047–1.520 | Additive | 0.002* | 1.729 | 1.215–2.459 | Dominant | 0.134 | 0.550 | 0.251–1.203 | Recessive | 0.002* | 1.440 | 1.143–1.814 | Dominant |
| rs3784737 | 0.220 | 1.165 | 0.913–1.485 | Dominant | 0.343 | 1.182 | 0.837–1.670 | Dominant | 0.041* | 1.485 | 1.017–2.170 | Dominant | 0.249 | 1.144 | 0.910–1.437 | Dominant |
| rs8037133 | 0.026* | 1.232 | 1.025–1.481 | Additive | 0.010* | 1.591 | 1.117–2.264 | Dominant | 0.394 | 0.744 | 0.378–1.467 | Recessive | 0.006* | 1.379 | 1.095–1.739 | Dominant |
| rs2168351 | 0.011* | 1.260 | 1.054–1.507 | Additive | 0.030* | 1.483 | 1.038–2.120 | Dominant | 0.959 | 0.985 | 0.553–1.755 | Recessive | 0.007* | 1.263 | 1.065–1.497 | Additive |
| rs3784731 | 0.021* | 1.656 | 1.080–2.540 | Recessive | 0.238 | 1.231 | 0.871–1.739 | Dominant | 0.583 | 0.900 | 0.619–1.310 | Dominant | 0.024* | 1.227 | 1.027–1.466 | Additive |
| rs1455777 | 0.014* | 1.266 | 1.048–1.529 | Additive | 0.119 | 1.318 | 0.932–1.865 | Dominant | 0.731 | 0.936 | 0.643–1.363 | Dominant | 0.011* | 1.261 | 1.055–1.508 | Additive |
| rs10775256 | 0.178 | 0.775 | 0.535–1.123 | Recessive | 0.213 | 0.708 | 0.410–1.220 | Recessive | 0.039* | 0.514 | 0.274–0.966 | Recessive | 0.125 | 0.763 | 0.539–1.078 | Recessive |
| rs897463 | 0.011* | 0.653 | 0.471–0.907 | Additive | 0.259 | 0.766 | 0.482–1.217 | Recessive | 0.490 | 0.464 | 0.052–4.102 | Recessive | 0.016* | 0.688 | 0.507–0.932 | Additive |
| rs7168443 | 0.029* | 0.702 | 0.511–0.965 | Additive | 0.431 | 0.837 | 0.538–1.303 | Recessive | 0.316 | 0.780 | 0.480–1.267 | Additive | 0.048* | 0.742 | 0.553–0.997 | Additive |
BD-I, bipolar I disorder; BD-II, bipolar II disorder; OR, odds ratio; CI, confidence interval
* p < 0.05
** corrected p < 0.05
a Nominal p-value by logistic regression with age and sex covariates.
b The inheritance model with the least Akaike Information Criterion was accepted as the best fitting model.