Table 3. Infection-related symptoms during human bocavirus 1 and 2 primary seroconversions compared with those of the previous and subsequent sampling intervals.
Primary HBoV1 immune responses, n = 64 | Primary HBoV2 immune responses, n = 44 | |||||||||
---|---|---|---|---|---|---|---|---|---|---|
SC interval | previous interval | next interval | SC interval | previous interval | next interval | |||||
Symptom | no. (%) | no. (%) | p value | no. (%) | p value | no (%) | no. (%) | p value | no. (%) | p value |
URTI | 29 (45) | 31 (48) | 0.86 | 20 (31) | 0.12 | 13 (30) | 14 (32) | 1.0 | 17 (39) | 0.50 |
Gastroenteritis | 14 (22) | 11 (17) | 0.66 | 10 (16) | 0.50 | 14 (32) | 6 (14) | 0.08 | 8 (18) | 0.24 |
Acute otitis media | 31 (48) | 20 (31) | 0.04* | 23 (36) | 0.20 | 12 (27) | 6 (14) | 0.18 | 12 (27) | 1.0 |
Note: first HBoV1 seroconversion was regarded as primary regardless of the presence or absence of pre-existing HBoV2 or -3 IgG, and vice versa. SC, seroconversion; URTI, upper respiratory tract illness; HBoV1, human bocavirus 1; HBoV2, human bocavirus 2.
Boldface and * indicate statistical significance by Liddell exact test (<0.05).