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. 2015 Sep 29;10(9):e0139096. doi: 10.1371/journal.pone.0139096

Table 3. Infection-related symptoms during human bocavirus 1 and 2 primary seroconversions compared with those of the previous and subsequent sampling intervals.

Primary HBoV1 immune responses, n = 64 Primary HBoV2 immune responses, n = 44
SC interval previous interval next interval SC interval previous interval next interval
Symptom no. (%) no. (%) p value no. (%) p value no (%) no. (%) p value no. (%) p value
URTI 29 (45) 31 (48) 0.86 20 (31) 0.12 13 (30) 14 (32) 1.0 17 (39) 0.50
Gastroenteritis 14 (22) 11 (17) 0.66 10 (16) 0.50 14 (32) 6 (14) 0.08 8 (18) 0.24
Acute otitis media 31 (48) 20 (31) 0.04* 23 (36) 0.20 12 (27) 6 (14) 0.18 12 (27) 1.0

Note: first HBoV1 seroconversion was regarded as primary regardless of the presence or absence of pre-existing HBoV2 or -3 IgG, and vice versa. SC, seroconversion; URTI, upper respiratory tract illness; HBoV1, human bocavirus 1; HBoV2, human bocavirus 2.

Boldface and * indicate statistical significance by Liddell exact test (<0.05).