Table 1.
Proposed clinical diagnostic criteria for CRPS (Budapest criteria)(Harden et al., 2010)⁎ | MedDRA Preferred terms or low level terms |
---|---|
Pain: continuing pain disproportionate to vaccination | Pain; pain in extremity |
Sensory: allodynia deep pressure pain, allodynia pain after movement, allodynia after light touch, hyperesthesia, hypoesthesia, hyperalgesia, hypoalgesia | Allodynia, hyperaesthesia, hypoaesthesia, sensory disturbance, skin burning sensation |
Vasomotor: color change/difference, temperature difference | Skin discoloration, temperature difference of extremities |
Sudomotor/edema: transpiration disturbance, edema | Oedema |
Trophic: hair growth change, nail growth change, trophic skin disturbance | Hair growth abnormal, nail growth abnormal |
Motor: limitation of movement, limitation of strength, dystonia, tremor, bradykinesia | Injection site movement impairment, injected limb mobility decreased, muscular weakness, dystonia, tremor, bradykinesia |
Pain should be continuous and disproportionate to the inciting event. In addition, for clinical diagnosis patients should have at least one symptom in each of the above categories and one sign in one category.