Table 1B.
Proteases/enzymes involved in the cleavage of Aβ peptide.
| Protease/enzyme | Description |
|---|---|
| ACE | Angiotensin-converting enzyme |
| CatB | Cathepsin B, a cysteine protease in lysosome |
| CatD | Cathepsin D, a cysteine protease in lysosome |
| ECE | Endothelin-converting enzyme |
| FXIa | Serine protease factor XIa |
| Gelatinase A | Secreted endopeptidase |
| IDE | Insulin-degrading enzyme |
| MMP-9 | Matrix metalloproteinase |
| NEP | Neprilysin, neutral endopeptidases |
| PreP | Presequence protease |
| The plasmin system | Components including plasmin and urokinase-type plasminogen activator (uPA), tissue plasminogen activator (tPA) |
| α2M complex | Serine protease-α2 macroglobulin complex |