Table 1.
Selection of commonly altered microRNAs in the peripheral blood of gastric cancer patients
| miRNA | Alteration | Sensitivity (%) | Specificity (%) | Ref. |
| miR1-8a | Up-regulated | 80.5 | 84.6 | [125] |
| miR-21 | Up-regulated | -1 | -1 | [134,202-205] |
| miR-187 | Up-regulated | 82.5 | 60.98 | [133] |
| miR-199a-3p | Up-regulated | 80.0 | 74.0 | [206,207] |
| miR-200c | Up-regulated | 65.4 | 100.0 | [122] |
| miR-371-5p | Up-regulated | 75.0 | 63.4 | [133] |
| miR-378 | Up-regulated | 87.5 | 70.7 | [133] |
| miR-451 | Up-regulated | 96.0 | 100.0 | [208] |
| miR-486 | Up-regulated | 86.0 | 97.0 | [208] |
| miR-223 and miR-21, miR-218 | miR-223 and miR-21 were up-regulated, miR-218 was down-regulated | 84.3 | 92.9 | [203] |
| miR-1, miR-20a, miR-27a, miR-34 and miR-423-5p | Up-regulated | 80.0 | 81.0 | [209] |
| miR-221, miR-744, and miR-376c | Up-regulated | 82.4 | 58.8 | [210] |
| miR-375, miR-142-5p | Up-regulated | > 85.0 | > 85.0 | [211] |
| miR-19b-3p, miR-16-5p | Up-regulated | 49.0 | 91.0 | [212] |
| 81.3 | 58.6 |
1
Different studies reported different sensitivity and specificity values.