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. 2015 Jul 29;5(3):275–298. doi: 10.3390/brainsci5030275

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© 2015 by the authors; licensee MDPI, Basel, Switzerland.

This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution license (http://creativecommons.org/licenses/by/4.0/).

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The utrophin/dystrophin protein complex and AChR. Acetylcholine Receptors (AChRs) are connected to the utrophin/dystrophin-associated protein complex by rapsyn, which is essential for AChR stabilization. AChR, acetylcholine receptor; ColQ, collagen Q; DG, dystroglycan; ErbB, erythroblastic leukemia viral oncogene homolog; LRP4, low-density lipoprotein receptor-related protein 4; MuSK, muscle-specific kinase; nNOS, neuronal nitric oxide synthase. This localization occurs at the neuromuscular junction.