a-b) Matrix of β-values showing dependences of functional brain connectivity with propofol level (a) and number of missed responses (b). c-d) Reduced connectivity matrix r for propofol (c) and missed responses (d). Blue connections represent negative Bn,m values, indicating a decrease in connectivity between systems n and m as the regressor increases, while red connections represent significantly positive Bn,m values, indicating a connectivity increase between systems n and m as regressor increases. e-f) Top ten ROIs with the highest average connectivity changes associated with propofol (e) and number of missed responses (f).