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. 2015 Jul 6;4(10):678–691. doi: 10.1016/j.molmet.2015.06.010

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© 2015 The Authors

This is an open access article under the CC BY license (http://creativecommons.org/licenses/by/4.0/).

PMC Copyright notice

Deletion of GluN2B in AgRP and POMC neurons: Pair-feeding and high-fat diet studies. (A) Body weight and cumulative food intake (weeks 3–9) of control (GluN2B^flox/flox) and AgRP-GluN2B KO female mice (n = 4–6/group). (B) Body weight and cumulative food intake (weeks 4–10) of control (GluN2B^flox/flox) and AgRP-GluN2B KO male mice and control (GluN2B^flox/flox) and POMC-GluN2B KO female mice during high-fat diet feeding. Data are shown as means ± SEM (n = 4–11/group). Repeated measures two-way ANOVA or Student's t test were conducted to evaluate differences between groups. NS: Not significant.