Table 1. The characterization of DOX loaded micelle.
| DOX loaded micelle | Size (nm) | Zeta potential (mV) | PDI | DL (%) | EE (%) | CMC (mg/L) |
|---|---|---|---|---|---|---|
| DOX loaded DOX-hyd-PEG-ALN micelle | 114 ± 17 | −19.3 ± 4.5 | 0.142 ± 0.008 | 24.3 ± 3.7 | 64.3 ± 8.9 | 2.4 ± 0.6 |
| DOX loaded DOX-hyd-PEG micelle | 278 ± 20 | −16.6 ± 3.8 | 0.265 ± 0.005 | 20.5 ± 2.5 | 55.6 ± 6.6 | 6.4 ± 1.7 |
DOX, doxorubicin; hyd, hydrazone; PEG, poly (ethylene glycol); ALN, alendronate; PDI, polydispersity index; DL, drug loading; EE, Encapsulation efficiency; CMC, critical micelle concentration. Data are mean ± SD (n = 3).