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. 2015 Sep 29;26(10):1026-1033. doi: 10.1097/CAD.0000000000000283

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Copyright © 2015 Wolters Kluwer Health, Inc. All rights reserved.

This is an open-access article distributed under the terms of the Creative Commons Attribution-Non Commercial-No Derivatives License 4.0 (CCBY-NC-ND), where it is permissible to download and share the work provided it is properly cited. The work cannot be changed in any way or used commercially. http://creativecommons.org/licenses/by-nc-nd/4.0/.

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Fig. 4 — Para-toluenesulfonamide (PTS) induces the release of mitochondrial cytochrome c and inhibits ATP biosynthesis. (a) Western blot analysis of Tca-8113 cells after 40 μmol/l PTS treatment for 1 h. Cytosolic cytochrome c released from mitochondria is shown. β-Actin was used as a loading control. (b) Tca-8113 cells were treated with 40 μmol/l PTS or dimethyl sulfoxide for 24–48 h. The effects of PTS on ATP biosynthesis were assessed by measuring chemiluminescence. Data represent the mean±SD of three independent experiments. *P<0.05.