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. 2015 Sep 30;8:498. doi: 10.1186/s13071-015-1108-7

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© Yin et al. 2015

Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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Fig. 4 — Adenovirus-vectored vaccine enhanced the cellular immune response in BALB/c mice. Ad-UMAS constructed using an adenovirus vector expressing the ubiquitin-conjugated MAS genes. The production levels of antibodies (IgG, IgG1 and IgG2a) (a), cytokines (IL-2, IL-10 and IFN-γ) (b), and splenocytes proliferation (c) were detected same as Fig. 2. *indicates statistically significant differences between Ad-UMAS vaccinated mice and p-UMAS vaccinated mice